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Cellular Uptake of the ATSM−Cu(II) Complex under Hypoxic Conditions

The Cu(II)‐diacetyl‐bis (N4‐methylthiosemicarbazone) complex (ATSM−Cu(II)) has been suggested as a promising positron emission tomography (PET) agent for hypoxia imaging. Several in‐vivo studies have shown its potential to detect hypoxic tumors. However, its uptake mechanism and its specificity to v...

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Detalles Bibliográficos
Autores principales: Walke, Gulshan R., Meron, Shelly, Shenberger, Yulia, Gevorkyan‐Airapetov, Lada, Ruthstein, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080296/
https://www.ncbi.nlm.nih.gov/pubmed/33908707
http://dx.doi.org/10.1002/open.202100044