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High-Yield Human Induced Pluripotent Stem Cell-Derived Monocytes and Macrophages Are Functionally Comparable With Primary Cells

Macrophages are pivotal effectors of host immunity and regulators of tissue homeostasis. Understanding of human macrophage biology has been hampered by the lack of reliable and scalable models for cellular and genetic studies. Human induced pluripotent stem cell (hiPSC)-derived monocytes and macroph...

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Detalles Bibliográficos
Autores principales: Cui, Di, Franz, Alexandra, Fillon, Sophie A., Jannetti, Linda, Isambert, Timo, Fundel-Clemens, Katrin, Huber, Heinrich J., Viollet, Coralie, Ghanem, Alexander, Niwa, Akira, Weigle, Bernd, Pflanz, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080307/
https://www.ncbi.nlm.nih.gov/pubmed/33937256
http://dx.doi.org/10.3389/fcell.2021.656867