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Tropomyosin 2.1 collaborates with fibronectin to promote TGF-β(1)-induced contraction of human lung fibroblasts

Many lung diseases are characterized by fibrosis, leading to impaired tissue patency and reduced lung function. Development of fibrotic tissue depends on two-way interaction between the cells and the extra-cellular matrix (ECM). Concentration-dependent increased stiffening of the ECM is sensed by th...

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Detalles Bibliográficos
Autores principales: Bradbury, Peta, Nader, Cassandra P., Cidem, Aylin, Rutting, Sandra, Sylvester, Dianne, He, Patrick, Rezcallah, Maria C., O’Neill, Geraldine M., Ammit, Alaina J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080347/
https://www.ncbi.nlm.nih.gov/pubmed/33910572
http://dx.doi.org/10.1186/s12931-021-01730-y