Tankyrases as modulators of pro-tumoral functions: molecular insights and therapeutic opportunities

Tankyrase 1 (TNKS1) and tankyrase 2 (TNKS2) are two homologous proteins that are gaining increasing importance due to their implication in multiple pathways and diseases such as cancer. TNKS1/2 interact with a large variety of substrates through the ankyrin (ANK) domain, which recognizes a sequence...

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Detalles Bibliográficos
Autores principales: Zamudio-Martinez, Esteban, Herrera-Campos, Ana Belén, Muñoz, Alberto, Rodríguez-Vargas, José Manuel, Oliver, F. Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080362/
https://www.ncbi.nlm.nih.gov/pubmed/33910596
http://dx.doi.org/10.1186/s13046-021-01950-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080362/
https://www.ncbi.nlm.nih.gov/pubmed/33910596
http://dx.doi.org/10.1186/s13046-021-01950-6

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