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Uncarboxylated osteocalcin alleviates the inhibitory effect of high glucose on osteogenic differentiation of mouse bone marrow–derived mesenchymal stem cells by regulating TP63

BACKGROUND: Progressive population aging has contributed to the increased global prevalence of diabetes and osteoporosis. Inhibition of osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) by hyperglycemia is a potential pathogenetic mechanism of osteoporosis in diabetic patients...

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Detalles Bibliográficos
Autores principales:	Gong, Fangzi, Gao, Le, Ma, Luyao, Li, Guangxin, Yang, Jianhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080387/ https://www.ncbi.nlm.nih.gov/pubmed/33906607 http://dx.doi.org/10.1186/s12860-021-00365-7

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