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Supramolecular co-assembly of self-adjuvanting nanofibrious peptide hydrogel enhances cancer vaccination by activating MyD88-dependent NF-κB signaling pathway without inflammation

Peptide vaccine targeting tumor-specific antigens is a promising cancer treatment regimen. However, peptide vaccines are commonly low-immunogenic, leading to suboptimal antitumor T-cell responses. Current peptide vaccination approaches are challenged by the variability of peptide physicochemical cha...

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Detalles Bibliográficos
Autores principales: Su, Qi, Song, Huijuan, Huang, Pingsheng, Zhang, Chuangnian, Yang, Jing, Kong, Deling, Wang, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080410/
https://www.ncbi.nlm.nih.gov/pubmed/33997486
http://dx.doi.org/10.1016/j.bioactmat.2021.03.041