Enzymatically active apurinic/apyrimidinic endodeoxyribonuclease 1 is released by mammalian cells through exosomes

The apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1), the main AP-endonuclease of the DNA base excision repair pathway, is a key molecule of interest to researchers due to its unsuspected roles in different nonrepair activities, such as: i) adaptive cell response to genotoxic stress, ii) regulat...

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Detalles Bibliográficos
Autores principales: Mangiapane, Giovanna, Parolini, Isabella, Conte, Kristel, Malfatti, Matilde Clarissa, Corsi, Jessica, Sanchez, Massimo, Pietrantoni, Agostina, D’Agostino, Vito G., Tell, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080531/
https://www.ncbi.nlm.nih.gov/pubmed/33753167
http://dx.doi.org/10.1016/j.jbc.2021.100569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080531/
https://www.ncbi.nlm.nih.gov/pubmed/33753167
http://dx.doi.org/10.1016/j.jbc.2021.100569

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