High prevalence of TP53 loss and whole-genome doubling in early-onset colorectal cancer

The global incidence of early-onset colorectal cancer (EO-CRC) is rapidly rising. However, the reason for this rise in incidence as well as the genomic characteristics of EO-CRC remain largely unknown. We performed whole-exome sequencing in 47 cases of EO-CRC and targeted deep sequencing in 833 case...

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Detalles Bibliográficos
Autores principales: Kim, Jeong Eun, Choi, Jaeyong, Sung, Chang-Ohk, Hong, Yong Sang, Kim, Sun Young, Lee, Hyunjung, Kim, Tae Won, Kim, Jong-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080557/
https://www.ncbi.nlm.nih.gov/pubmed/33753878
http://dx.doi.org/10.1038/s12276-021-00583-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080557/
https://www.ncbi.nlm.nih.gov/pubmed/33753878
http://dx.doi.org/10.1038/s12276-021-00583-1

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