Melatonin prevents doxorubicin-induced cardiotoxicity through suppression of AMPKα2-dependent mitochondrial damage

The clinical application of doxorubicin, one of the most effective anticancer drugs, has been limited due to its adverse effects, including cardiotoxicity. One of the hallmarks of doxorubicin-induced cytotoxicity is mitochondrial dysfunction. Despite intensive research over recent decades, there are...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Goowon, Song, Minhyeok, Hoang, Dang Hieu, Tran, Quynh Hoa, Choe, Wonchae, Kang, Insug, Kim, Sung Soo, Ha, Joohun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080573/
https://www.ncbi.nlm.nih.gov/pubmed/33339952
http://dx.doi.org/10.1038/s12276-020-00541-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080573/
https://www.ncbi.nlm.nih.gov/pubmed/33339952
http://dx.doi.org/10.1038/s12276-020-00541-3

Ejemplares similares