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Unraveling the stability landscape of mutations in the SARS-CoV-2 receptor-binding domain

The interaction between the receptor-binding domain (RBD) of the SARS-CoV-2 spike glycoprotein and the ACE2 enzyme is believed to be the entry point of the virus into various cells in the body, including the lungs, heart, liver, and kidneys. The current focus of several therapeutic design efforts ex...

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Detalles Bibliográficos
Autores principales: Smaoui, Mohamed Raef, Yahyaoui, Hamdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080587/
https://www.ncbi.nlm.nih.gov/pubmed/33911163
http://dx.doi.org/10.1038/s41598-021-88696-5