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Modulation of α(V)β(6) integrin in osteoarthritis-related synovitis and the interaction with VTN((381–397 a.a.)) competing for TGF-β1 activation
Osteoarthritis is characterized by structural alteration of joints. Fibrosis of the synovial tissue is often detected and considered one of the main causes of joint stiffness and pain. In our earlier proteomic study, increased levels of vitronectin (VTN) fragment (amino acids 381–397) were observed...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080589/ https://www.ncbi.nlm.nih.gov/pubmed/33526813 http://dx.doi.org/10.1038/s12276-021-00558-2 |