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Modulation of α(V)β(6) integrin in osteoarthritis-related synovitis and the interaction with VTN((381–397 a.a.)) competing for TGF-β1 activation

Osteoarthritis is characterized by structural alteration of joints. Fibrosis of the synovial tissue is often detected and considered one of the main causes of joint stiffness and pain. In our earlier proteomic study, increased levels of vitronectin (VTN) fragment (amino acids 381–397) were observed...

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Detalles Bibliográficos
Autores principales: Ciregia, Federica, Deroyer, Céline, Cobraiville, Gaël, Plener, Zelda, Malaise, Olivier, Gillet, Philippe, Fillet, Marianne, Malaise, Michel G., de Seny, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080589/
https://www.ncbi.nlm.nih.gov/pubmed/33526813
http://dx.doi.org/10.1038/s12276-021-00558-2