A novel framework for engineering protein loops exploring length and compositional variation

Insertions and deletions (indels) are known to affect function, biophysical properties and substrate specificity of enzymes, and they play a central role in evolution. Despite such clear significance, this class of mutation remains an underexploited tool in protein engineering with few available pla...

Descripción completa

Detalles Bibliográficos
Autores principales: Tizei, Pedro A. G., Harris, Emma, Withanage, Shamal, Renders, Marleen, Pinheiro, Vitor B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080606/
https://www.ncbi.nlm.nih.gov/pubmed/33911147
http://dx.doi.org/10.1038/s41598-021-88708-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080606/
https://www.ncbi.nlm.nih.gov/pubmed/33911147
http://dx.doi.org/10.1038/s41598-021-88708-4

Ejemplares similares