Selective deletion of SHIP-1 in hematopoietic cells in mice leads to severe lung inflammation involving ILC2 cells

Src homology 2 domain–containing inositol 5-phosphatase 1 (SHIP-1) regulates the intracellular levels of phosphotidylinositol-3, 4, 5-trisphosphate, a phosphoinositide 3–kinase (PI3K) product. Emerging evidence suggests that the PI3K pathway is involved in allergic inflammation in the lung. Germline...

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Detalles Bibliográficos
Autores principales: Ye, Xujun, Zhang, Fengrui, Zhou, Li, Wei, Yadong, Zhang, Li, Wang, Lihui, Tang, Haiying, Chen, Zi, Kerr, William G., Zheng, Tao, Zhu, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080607/
https://www.ncbi.nlm.nih.gov/pubmed/33911168
http://dx.doi.org/10.1038/s41598-021-88677-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080607/
https://www.ncbi.nlm.nih.gov/pubmed/33911168
http://dx.doi.org/10.1038/s41598-021-88677-8

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