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METTL3 promotes adriamycin resistance in MCF-7 breast cancer cells by accelerating pri-microRNA-221-3p maturation in a m6A-dependent manner

Breast cancer (BC) is the most prevalent malignant neoplasm among women and is the fifth most common cause of cancer-associated death worldwide. Acquired chemoresistance driven by genetic and epigenetic alterations is a significant clinical challenge in treating BC. However, the mechanism of BC cell...

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Detalles Bibliográficos
Autores principales: Pan, Xiaoping, Hong, Xiaolv, Li, Sumei, Meng, Ping, Xiao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080609/
https://www.ncbi.nlm.nih.gov/pubmed/33420414
http://dx.doi.org/10.1038/s12276-020-00510-w