Delta-secretase cleavage of Tau mediates its pathology and propagation in Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease with age as a major risk factor. AD is the most common dementia with abnormal structures, including extracellular senile plaques and intraneuronal neurofibrillary tangles, as key neuropathologic hallmarks. The early feature of AD pa...

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Detalles Bibliográficos
Autores principales: Kang, Seong Su, Ahn, Eun Hee, Ye, Keqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080617/
https://www.ncbi.nlm.nih.gov/pubmed/32859953
http://dx.doi.org/10.1038/s12276-020-00494-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080617/
https://www.ncbi.nlm.nih.gov/pubmed/32859953
http://dx.doi.org/10.1038/s12276-020-00494-7

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