Cargando…

β2-adrenergic receptor agonist counteracts skeletal muscle atrophy and oxidative stress in uremic mice

In patients with chronic kidney disease, skeletal muscle dysfunction is associated with mortality. Uremic sarcopenia is caused by ageing, malnutrition, and chronic inflammation, but the molecular mechanism and potential therapeutics have not been fully elucidated yet. We hypothesize that accumulated...

Descripción completa

Detalles Bibliográficos
Autores principales: Higashihara, Takaaki, Nishi, Hiroshi, Takemura, Koji, Watanabe, Hiroshi, Maruyama, Toru, Inagi, Reiko, Tanaka, Tetsuhiro, Nangaku, Masaomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080640/
https://www.ncbi.nlm.nih.gov/pubmed/33911115
http://dx.doi.org/10.1038/s41598-021-88438-7