Global transcriptional downregulation of TREX and nuclear trafficking machinery as pan-senescence phenomena: evidence from human cells and tissues

Nucleocytoplasmic trafficking (NCT) of macromolecules is a fundamental process in eukaryotes that requires tight controls to maintain proper cell functions. Downregulation of the classical NCT pathway in senescent cells has been reported. However, whether this is a hallmark that exists across all ty...

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Detalles Bibliográficos
Autores principales: Kim, Sung Young, Yang, Eun Jae, Lee, Sung Bae, Lee, Young-Sam, Cho, Kyoung A., Park, Sang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080647/
https://www.ncbi.nlm.nih.gov/pubmed/32859952
http://dx.doi.org/10.1038/s12276-020-00490-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080647/
https://www.ncbi.nlm.nih.gov/pubmed/32859952
http://dx.doi.org/10.1038/s12276-020-00490-x

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