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A survey of the kinome pharmacopeia reveals multiple scaffolds and targets for the development of novel anthelmintics

Over one billion people are currently infected with a parasitic nematode. Symptoms can include anemia, malnutrition, developmental delay, and in severe cases, death. Resistance is emerging to the anthelmintics currently used to treat nematode infection, prompting the need to develop new anthelmintic...

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Detalles Bibliográficos
Autores principales: Knox, Jessica, Joly, Nicolas, Linossi, Edmond M., Carmona-Negrón, José A., Jura, Natalia, Pintard, Lionel, Zuercher, William, Roy, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080662/
https://www.ncbi.nlm.nih.gov/pubmed/33911106
http://dx.doi.org/10.1038/s41598-021-88150-6