FGF401 and vinorelbine synergistically mediate antitumor activity and vascular normalization in FGF19-dependent hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a lethal cancer with limited therapeutic options, and standard therapy with sorafenib provides only modest survival benefits. Fibroblast growth factor 19 (FGF19) has been proposed as a driver oncogene, and targeting its receptor, FGFR-4, may provide a better alterna...

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Detalles Bibliográficos
Autores principales: Huynh, Hung, Prawira, Aldo, Le, Thi Bich Uyen, Vu, Thanh Chung, Hao, Huai-Xiang, Huang, Alan, Wang, Youzhen, Porta, Diana Graus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080677/
https://www.ncbi.nlm.nih.gov/pubmed/33235319
http://dx.doi.org/10.1038/s12276-020-00524-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080677/
https://www.ncbi.nlm.nih.gov/pubmed/33235319
http://dx.doi.org/10.1038/s12276-020-00524-4

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