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FGF401 and vinorelbine synergistically mediate antitumor activity and vascular normalization in FGF19-dependent hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a lethal cancer with limited therapeutic options, and standard therapy with sorafenib provides only modest survival benefits. Fibroblast growth factor 19 (FGF19) has been proposed as a driver oncogene, and targeting its receptor, FGFR-4, may provide a better alterna...
Autores principales: | Huynh, Hung, Prawira, Aldo, Le, Thi Bich Uyen, Vu, Thanh Chung, Hao, Huai-Xiang, Huang, Alan, Wang, Youzhen, Porta, Diana Graus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080677/ https://www.ncbi.nlm.nih.gov/pubmed/33235319 http://dx.doi.org/10.1038/s12276-020-00524-4 |
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