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Rad50 mediates DNA demethylation to establish pluripotent reprogramming
DNA demethylation is characterized by the loss of methyl groups from 5-methylcytosine, and this activity is involved in various biological processes in mammalian cell development and differentiation. In particular, dynamic DNA demethylation in the process of somatic cell reprogramming is required fo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080709/ https://www.ncbi.nlm.nih.gov/pubmed/32665583 http://dx.doi.org/10.1038/s12276-020-0467-0 |