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GSK3B induces autophagy by phosphorylating ULK1

Unc-51-like autophagy activating kinase 1 (ULK1), a mammalian homolog of the yeast kinase Atg1, has an essential role in autophagy induction. In nutrient and growth factor signaling, ULK1 activity is regulated by various posttranslational modifications, including phosphorylation, acetylation, and ub...

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Detalles Bibliográficos
Autores principales: Ryu, Hye Young, Kim, Leah Eunjung, Jeong, Hyeonjeong, Yeo, Bo Kyoung, Lee, Ji-Won, Nam, Hyeri, Ha, Shinwon, An, Hyun-Kyu, Park, Hyunhee, Jung, Seonghee, Chung, Kyung Min, Kim, Jiyea, Lee, Byung-Hoon, Cheong, Heesun, Kim, Eun-Kyoung, Yu, Seong-Woon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080724/
https://www.ncbi.nlm.nih.gov/pubmed/33654220
http://dx.doi.org/10.1038/s12276-021-00570-6