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Ryk modulates the niche activity of mesenchymal stromal cells by fine-tuning canonical Wnt signaling
The importance of modulating the intensity of Wnt signaling has been highlighted in various biological models, but their mechanisms remain unclear. In this study, we found that Ryk—an atypical Wnt receptor with a pseudokinase domain—has a Wnt-modulating effect in bone marrow stromal cells to control...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080773/ https://www.ncbi.nlm.nih.gov/pubmed/32724069 http://dx.doi.org/10.1038/s12276-020-0477-y |