The dopamine D1–D2DR complex in the rat spinal cord promotes neuropathic pain by increasing neuronal excitability after chronic constriction injury

Dopamine D1 receptor (D1DR) and D2 receptor (D2DR) are closely associated with pain modulation, but their exact effects on neuropathic pain and the underlying mechanisms remain to be identified. Our research revealed that intrathecal administration of D1DR and D2DR antagonists inhibited D1–D2DR comp...

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Detalles Bibliográficos
Autores principales: Bao, Yi-Ni, Dai, Wen-Ling, Fan, Ji-Fa, Ma, Bin, Li, Shan-Shan, Zhao, Wan-Li, Yu, Bo-Yang, Liu, Ji-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080784/
https://www.ncbi.nlm.nih.gov/pubmed/33558591
http://dx.doi.org/10.1038/s12276-021-00563-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080784/
https://www.ncbi.nlm.nih.gov/pubmed/33558591
http://dx.doi.org/10.1038/s12276-021-00563-5

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