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Effects of innate immune receptor stimulation on extracellular α-synuclein uptake and degradation by brain resident cells
Synucleinopathies are age-related neurological disorders characterized by the progressive deposition of α-synuclein (α-syn) aggregates and include Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Although cell-to-cell α-syn transmission is thought to play a key role in the spread of α-s...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080790/ https://www.ncbi.nlm.nih.gov/pubmed/33594256 http://dx.doi.org/10.1038/s12276-021-00562-6 |