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Disentangling age-dependent DNA methylation: deterministic, stochastic, and nonlinear

DNA methylation variability arises due to concurrent genetic and environmental influences. Each of them is a mixture of regular and noisy sources, whose relative contribution has not been satisfactorily understood yet. We conduct a systematic assessment of the age-dependent methylation by the signal...

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Detalles Bibliográficos
Autores principales: Vershinina, O., Bacalini, M. G., Zaikin, A., Franceschi, C., Ivanchenko, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8080842/
https://www.ncbi.nlm.nih.gov/pubmed/33911141
http://dx.doi.org/10.1038/s41598-021-88504-0