Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein

The spike protein receptor-binding domain (RBD) of SARS-CoV-2 is the molecular target for many vaccines and antibody-based prophylactics aimed at bringing COVID-19 under control. Such a narrow molecular focus raises the specter of viral immune evasion as a potential failure mode for these biomedical...

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Detalles Bibliográficos
Autores principales: Van Egeren, Debra, Novokhodko, Alexander, Stoddard, Madison, Tran, Uyen, Zetter, Bruce, Rogers, Michael, Pentelute, Bradley L., Carlson, Jonathan M., Hixon, Mark, Joseph-McCarthy, Diane, Chakravarty, Arijit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081162/
https://www.ncbi.nlm.nih.gov/pubmed/33909660
http://dx.doi.org/10.1371/journal.pone.0250780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081162/
https://www.ncbi.nlm.nih.gov/pubmed/33909660
http://dx.doi.org/10.1371/journal.pone.0250780

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