Improving the Thermostability and Activity of Transaminase From Aspergillus terreus by Charge-Charge Interaction

Transaminases that promote the amination of ketones into amines are an emerging class of biocatalysts for preparing a series of drugs and their intermediates. One of the main limitations of (R)-selective amine transaminase from Aspergillus terreus (At-ATA) is its weak thermostability, with a half-li...

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Detalles Bibliográficos
Autores principales: Cao, Jia-Ren, Fan, Fang-Fang, Lv, Chang-Jiang, Wang, Hong-Peng, Li, Ye, Hu, Sheng, Zhao, Wei-Rui, Chen, Hai-Bin, Huang, Jun, Mei, Le-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081293/
https://www.ncbi.nlm.nih.gov/pubmed/33937200
http://dx.doi.org/10.3389/fchem.2021.664156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081293/
https://www.ncbi.nlm.nih.gov/pubmed/33937200
http://dx.doi.org/10.3389/fchem.2021.664156

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