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Improving the Thermostability and Activity of Transaminase From Aspergillus terreus by Charge-Charge Interaction
Transaminases that promote the amination of ketones into amines are an emerging class of biocatalysts for preparing a series of drugs and their intermediates. One of the main limitations of (R)-selective amine transaminase from Aspergillus terreus (At-ATA) is its weak thermostability, with a half-li...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081293/ https://www.ncbi.nlm.nih.gov/pubmed/33937200 http://dx.doi.org/10.3389/fchem.2021.664156 |