Ascorbate-dependent and ascorbate-independent Mn porphyrin cytotoxicity: anticancer activity of Mn porphyrin-based SOD mimics through ascorbate-dependent and -independent routes

OBJECTIVE: The aim of this study was to investigate how modifications at the periphery of the porphyrin ring affect the anticancer activity of Mn porphyrins (MnPs)-based SOD mimics. METHODS: Six compounds: MnTE-2-PyP with a short ethyl chain on the pyridyl ring; MnTnHexOE-2-PyP and MnTnOct-2-PyP wit...

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Detalles Bibliográficos
Autores principales: Hasan, Bader, Tovmasyan, Artak, Batinic-Haberle, Ines, Benov, Ludmil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081310/
https://www.ncbi.nlm.nih.gov/pubmed/33902399
http://dx.doi.org/10.1080/13510002.2021.1917214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081310/
https://www.ncbi.nlm.nih.gov/pubmed/33902399
http://dx.doi.org/10.1080/13510002.2021.1917214

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