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PAR2 Promoter Hypomethylation Regulates PAR2 Gene Expression and Promotes Lung Adenocarcinoma Cell Progression

OBJECTIVE: Protease-activated receptor-2 (PAR2) also known as F2RL1 is a G protein-coupled receptor that intimately correlates with cancer occurrence. DNA methylation turns out a vital mechanism regulating gene expression, while PAR2 promoter methylation is proven to be involved in cancer developmen...

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Detalles Bibliográficos
Autores principales: Wu, Kuan, Xu, Lei, Cheng, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081642/
https://www.ncbi.nlm.nih.gov/pubmed/33968158
http://dx.doi.org/10.1155/2021/5542485