Intranasal delivery of BDNF rescues memory deficits in AD11 mice and reduces brain microgliosis

A decrease in brain-derived neurotrophic factor (BDNF), a neurotrophin essential for synaptic function, plasticity and neuronal survival, is evident early in the progression of Alzheimer’s disease (AD), being apparent in subjects with mild cognitive impairment or mild AD, and both proBDNF and mature...

Descripción completa

Detalles Bibliográficos
Autores principales: Braschi, Chiara, Capsoni, Simona, Narducci, Roberta, Poli, Andrea, Sansevero, Gabriele, Brandi, Rossella, Maffei, Lamberto, Cattaneo, Antonino, Berardi, Nicoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081712/
https://www.ncbi.nlm.nih.gov/pubmed/32676979
http://dx.doi.org/10.1007/s40520-020-01646-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081712/
https://www.ncbi.nlm.nih.gov/pubmed/32676979
http://dx.doi.org/10.1007/s40520-020-01646-5

Ejemplares similares