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The Impact of ABCB1 and CES1 Polymorphisms on Dabigatran Pharmacokinetics in Healthy Chinese Subjects

Dabigatran is a novel direct oral anticoagulant agent, whose plasma concentration is closely related to bleeding risk. Genetic polymorphisms can affect the level of plasma dabigatran. The purpose of this study was to understand the relationship between dabigatran-related genes and the plasma level o...

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Detalles Bibliográficos
Autores principales: Liu, Yue, Yang, Chenguang, Qi, Wenyuan, Pei, Zuowei, Xue, Wei, Zhu, Huolan, Dong, Min, Guo, Ying, Cong, Duanduan, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081719/
https://www.ncbi.nlm.nih.gov/pubmed/33935512
http://dx.doi.org/10.2147/PGPM.S291723