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The Impact of ABCB1 and CES1 Polymorphisms on Dabigatran Pharmacokinetics in Healthy Chinese Subjects
Dabigatran is a novel direct oral anticoagulant agent, whose plasma concentration is closely related to bleeding risk. Genetic polymorphisms can affect the level of plasma dabigatran. The purpose of this study was to understand the relationship between dabigatran-related genes and the plasma level o...
Autores principales: | Liu, Yue, Yang, Chenguang, Qi, Wenyuan, Pei, Zuowei, Xue, Wei, Zhu, Huolan, Dong, Min, Guo, Ying, Cong, Duanduan, Wang, Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081719/ https://www.ncbi.nlm.nih.gov/pubmed/33935512 http://dx.doi.org/10.2147/PGPM.S291723 |
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