Extended haplotype-phasing of long-read de novo genome assemblies using Hi-C

Haplotype-resolved genome assemblies are important for understanding how combinations of variants impact phenotypes. To date, these assemblies have been best created with complex protocols, such as cultured cells that contain a single-haplotype (haploid) genome, single cells where haplotypes are sep...

Descripción completa

Detalles Bibliográficos
Autores principales: Kronenberg, Zev N., Rhie, Arang, Koren, Sergey, Concepcion, Gregory T., Peluso, Paul, Munson, Katherine M., Porubsky, David, Kuhn, Kristen, Mueller, Kathryn A., Low, Wai Yee, Hiendleder, Stefan, Fedrigo, Olivier, Liachko, Ivan, Hall, Richard J., Phillippy, Adam M., Eichler, Evan E., Williams, John L., Smith, Timothy P. L., Jarvis, Erich D., Sullivan, Shawn T., Kingan, Sarah B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081726/
https://www.ncbi.nlm.nih.gov/pubmed/33911078
http://dx.doi.org/10.1038/s41467-020-20536-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081726/
https://www.ncbi.nlm.nih.gov/pubmed/33911078
http://dx.doi.org/10.1038/s41467-020-20536-y

Ejemplares similares