The Potent Trypanocidal Effect of LQB303, a Novel Redox-Active Phenyl-Tert-Butyl-Nitrone Derivate That Causes Mitochondrial Collapse in Trypanosoma cruzi

Chagas disease, which is caused by Trypanosoma cruzi, establishes lifelong infections in humans and other mammals that lead to severe cardiac and gastrointestinal complications despite the competent immune response of the hosts. Furthermore, it is a neglected disease that affects 8 million people wo...

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Detalles Bibliográficos
Autores principales: Macedo, Carolina Machado, Saraiva, Francis Monique de Souza, Paula, Jéssica Isis Oliveira, Nascimento, Suelen de Brito, Costa, Débora de Souza dos Santos, Costa, Paulo Roberto Ribeiro, Dias, Ayres Guimarães, Paes, Marcia Cristina, Nogueira, Natália Pereira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081855/
https://www.ncbi.nlm.nih.gov/pubmed/33935988
http://dx.doi.org/10.3389/fmicb.2021.617504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081855/
https://www.ncbi.nlm.nih.gov/pubmed/33935988
http://dx.doi.org/10.3389/fmicb.2021.617504

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