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DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response
Viruses and hosts have coevolved for millions of years, leading to the development of complex host–pathogen interactions. Influenza A virus (IAV) causes severe pulmonary pathology and is a recurrent threat to human health. Innate immune sensing of IAV triggers a complex chain of host responses. IAV...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081917/ https://www.ncbi.nlm.nih.gov/pubmed/33766561 http://dx.doi.org/10.1016/j.jbc.2021.100579 |