Cargando…

Super hotspots and super coldspots in the repair of UV-induced DNA damage in the human genome

The formation of UV-induced DNA damage and its repair are influenced by many factors that modulate lesion formation and the accessibility of repair machinery. However, it remains unknown which genomic sites are prioritized for immediate repair after UV damage induction, and whether these prioritized...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Yuchao, Li, Wentao, Lindsey-Boltz, Laura A., Yang, Yuchen, Li, Yun, Sancar, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081918/
https://www.ncbi.nlm.nih.gov/pubmed/33771559
http://dx.doi.org/10.1016/j.jbc.2021.100581