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一种新的靶向CD19抗原的三特异性T细胞衔接器的制备及其抗白血病作用研究
OBJECTIVE: To prepare a novel tri-specific T cell engager(19TriTE)targeting CD19 antigen, and to investigate its immunotherapeutic effect on CD19-positive hematological malignancies. METHODS: 19TriTE was constructed by molecular cloning technology and successfully expressed through the eukaryotic ex...
Formato: | Online Artículo Texto |
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Lenguaje: | English |
Publicado: |
Editorial office of Chinese Journal of Hematology
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081940/ https://www.ncbi.nlm.nih.gov/pubmed/33910307 http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2021.03.007 |