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Enhancing Fatty Acid Catabolism of Macrophages Within Aberrant Breast Cancer Tumor Microenvironment Can Re-establish Antitumor Function

Triple-negative breast cancer (TNBC) remains an intractable challenge owing to its aggressive nature and lack of any known therapeutic targets. Macrophages play a crucial role in cancer promotion and poor prognosis within the tumor microenvironment (TME). The phagocytosis checkpoint in macrophages h...

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Detalles Bibliográficos
Autores principales: Gu, Yucui, Niu, Xingjian, Yin, Lei, Wang, Yiran, Yang, Yue, Yang, Xudong, Zhang, Qingyuan, Ji, Hongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081981/
https://www.ncbi.nlm.nih.gov/pubmed/33937269
http://dx.doi.org/10.3389/fcell.2021.665869