Cargando…
Generation of a squamous cell carcinoma mouse model for lineage tracing of BMI1+ cancer stem cells
BMI1-expressing cancer stem cells (CSCs) play a key role in the development, progression, therapy resistance, recurrence, and metastasis of head and neck squamous cell carcinoma (HNSCC). Here, we present a chemically-induced HNSCC mouse model, genetically and pathologically similar to human HNSCC. T...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081985/ https://www.ncbi.nlm.nih.gov/pubmed/33982017 http://dx.doi.org/10.1016/j.xpro.2021.100484 |