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Generation of a squamous cell carcinoma mouse model for lineage tracing of BMI1+ cancer stem cells

BMI1-expressing cancer stem cells (CSCs) play a key role in the development, progression, therapy resistance, recurrence, and metastasis of head and neck squamous cell carcinoma (HNSCC). Here, we present a chemically-induced HNSCC mouse model, genetically and pathologically similar to human HNSCC. T...

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Detalles Bibliográficos
Autores principales:	Chen, Demeng, Zhang, Wuchang, Jia, Lingfei, Wang, Cheng, Wang, Cun-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8081985/ https://www.ncbi.nlm.nih.gov/pubmed/33982017 http://dx.doi.org/10.1016/j.xpro.2021.100484

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