SARS-CoV-2 Infection Induces Psoriatic Arthritis Flares and Enthesis Resident Plasmacytoid Dendritic Cell Type-1 Interferon Inhibition by JAK Antagonism Offer Novel Spondyloarthritis Pathogenesis Insights

OBJECTIVE: Bacterial and viral infectious triggers are linked to spondyloarthritis (SpA) including psoriatic arthritis (PsA) development, likely via dendritic cell activation. We investigated spinal entheseal plasmacytoid dendritic cells (pDCs) toll-like receptor (TLR)-7 and 9 activation and therape...

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Detalles Bibliográficos
Autores principales: Zhou, Qiao, Vadakekolathu, Jayakumar, Watad, Abdulla, Sharif, Kassem, Russell, Tobias, Rowe, Hannah, Khan, Almas, Millner, Peter A., Loughenbury, Peter, Rao, Abhay, Dunsmuir, Robert, Timothy, Jake, Damiani, Giovanni, Pigatto, Paolo D. M., Malagoli, Piergiorgio, Banfi, Giuseppe, El-Sherbiny, Yasser M., Bridgewood, Charlie, McGonagle, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082065/
https://www.ncbi.nlm.nih.gov/pubmed/33936047
http://dx.doi.org/10.3389/fimmu.2021.635018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082065/
https://www.ncbi.nlm.nih.gov/pubmed/33936047
http://dx.doi.org/10.3389/fimmu.2021.635018

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