Cargando…

SIRT1 Deacetylates TET2 and Promotes Its Ubiquitination Degradation to Achieve Neuroprotection Against Parkinson's Disease

The epigenetic modifications, such as DNA methylation and histone acetylation, play a critical role in the pathogenesis of Parkinson's disease (PD). However, the relationship between DNA methylation and histone acetylation in PD is not fully understood. Previous studies have shown that patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xuan, Liu, Te, Wu, Ting-Ting, Feng, Ya, Peng, Si-Jia, Yin, Huiyong, Wu, Yun-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082066/
https://www.ncbi.nlm.nih.gov/pubmed/33935952
http://dx.doi.org/10.3389/fneur.2021.652882