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LECT 2 Antagonizes FOXM1 Signaling via Inhibiting MET to Retard PDAC Progression

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers with minimally effective treatments, highlighting the importance of developing novel biomarkers and therapeutic targets. Here, we disclosed the mechanisms that leukocyte cell-derived chemotaxin-2 (LECT2) modulates PDAC develop...

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Detalles Bibliográficos
Autores principales: Li, Xin, Lin, Pingping, Tao, Ye, Jiang, Xin, Li, Ting, Wang, Yunshan, Wang, Chenjing, Cao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082113/
https://www.ncbi.nlm.nih.gov/pubmed/33937262
http://dx.doi.org/10.3389/fcell.2021.661122