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Multicellular “hotspots” harbor high-grade potential in lower-grade gliomas

BACKGROUND: Lower-grade gliomas may be indolent for many years before developing malignant behavior. The mechanisms underlying malignant progression remain unclear. METHODS: We collected blocks of live human brain tissue donated by people undergoing glioma resection. The tissue blocks extended throu...

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Detalles Bibliográficos
Autores principales: Kirby, Alastair J, Lavrador, José P, Bodi, Istvan, Vergani, Francesco, Bhangoo, Ranjeev, Ashkan, Keyoumars, Finnerty, Gerald T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082133/
https://www.ncbi.nlm.nih.gov/pubmed/33959713
http://dx.doi.org/10.1093/noajnl/vdab026