Bexarotene Impairs Cognition and Produces Hypothyroidism in a Mouse Model of Down Syndrome and Alzheimer’s Disease

All individuals with Down syndrome (DS) eventually develop Alzheimer’s disease (AD) neuropathology, including neurodegeneration, increases in β-amyloid (Aβ) expression, and aggregation and neurofibrillary tangles, between the third and fourth decade of their lives. There is currently no effective tr...

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Detalles Bibliográficos
Autores principales: Vidal, Verónica, Puente, Alba, García-Cerro, Susana, García Unzueta, María Teresa, Rueda, Noemí, Riancho, Javier, Martínez-Cué, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082148/
https://www.ncbi.nlm.nih.gov/pubmed/33935706
http://dx.doi.org/10.3389/fphar.2021.613211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082148/
https://www.ncbi.nlm.nih.gov/pubmed/33935706
http://dx.doi.org/10.3389/fphar.2021.613211

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