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Luteolin Ameliorates Experimental Pulmonary Arterial Hypertension via Suppressing Hippo-YAP/PI3K/AKT Signaling Pathway

Luteolin is a flavonoid compound with a variety of pharmacological effects. In this study, we explored the effects of luteolin on monocrotaline (MCT) induced rat pulmonary arterial hypertension (PAH) and underlying mechanisms. A rat PAH model was generated through MCT injection. In this model, luteo...

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Detalles Bibliográficos
Autores principales: Zuo, Wanyun, Liu, Na, Zeng, Yunhong, Xiao, Zhenghui, Wu, Keke, Yang, Fan, Li, Biao, Song, Qingqing, Xiao, Yunbin, Liu, Qiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082250/
https://www.ncbi.nlm.nih.gov/pubmed/33935785
http://dx.doi.org/10.3389/fphar.2021.663551