Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal Stem Cells

BACKGROUND & AIMS: aISCs (aISCs) are sensitive to acute insults including chemotherapy and irradiation. Regeneration after aISC depletion has primarily been explored in irradiation (IR). However, the cellular origin of epithelial regeneration after doxorubicin (DXR), a common chemotherapeutic, i...

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Detalles Bibliográficos
Autores principales: Sheahan, Breanna J., Freeman, Ally N., Keeley, Theresa M., Samuelson, Linda C., Roper, Jatin, Hasapis, Stephanie, Lee, Chang-Lung, Dekaney, Christopher M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082264/
https://www.ncbi.nlm.nih.gov/pubmed/33571711
http://dx.doi.org/10.1016/j.jcmgh.2021.01.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082264/
https://www.ncbi.nlm.nih.gov/pubmed/33571711
http://dx.doi.org/10.1016/j.jcmgh.2021.01.015

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