Cannabinoid type 1 receptor inverse agonism attenuates dyslipidemia and atherosclerosis in APOE∗3-Leiden.CETP mice

Pharmacological blockade of the cannabinoid type 1 receptor, a G protein-coupled receptor expressed in the central nervous system and various peripheral tissues, reverses diet-induced obesity and dyslipidemia through the reduction of food intake and altered nutrient partitioning. This strategy is be...

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Detalles Bibliográficos
Autores principales: van Eenige, Robin, Ying, Zhixiong, Tambyrajah, Lauren, Pronk, Amanda C.M., Blomberg, Niek, Giera, Martin, Wang, Yanan, Coskun, Tamer, van der Stelt, Mario, Rensen, Patrick C.N., Kooijman, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082266/
https://www.ncbi.nlm.nih.gov/pubmed/33766515
http://dx.doi.org/10.1016/j.jlr.2021.100070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082266/
https://www.ncbi.nlm.nih.gov/pubmed/33766515
http://dx.doi.org/10.1016/j.jlr.2021.100070

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